Calibrin®-Z disminuye los efectos negativos de múltiples micotoxinas: aflatoxinas, fumonisinas y toxina T-2 en pollos de engorda

Resumen

Multiple mycotoxins naturally produced by fungus usually coexist in grains. Calibrin-Z® (Amlan International, Chicago, IL, available in select international markets) is a calcium montmorillonite that has been shown to bind toxins. A total of 240 one-day-old male Cobb 500 broiler chicks with an average weight of 44.67 g was used in a 21-day experiment to evaluate the effect of Calibrin-Z and Product Y on chicks fed a diet contaminated with multiple mycotoxins. A completely randomized trial was conducted with 4 treatments in 6 pens per treatment and 10 birds in each pen. Statistical analysis was conducted using the Student T test in JMP software v15.0. Statistical significance was set at P<0.05. The treatments were: 1) Unchallenged control; 2) Challenged control with 1.8 ppm Aflatoxins, 50 ppm Fumonisin and 1 ppm T-2 Toxin; 3) Challenged control with 0.5 % Calibrin-Z; and 4) Challenged control with 0.5 % Product Y. The diet was corn-soybean meal-based and met the requirements in the Cobb Broiler Management Guide. No major mycotoxins were detected when raw materials were screened. Birds fed multi-toxins with Calibrin-Z, but not Product Y had higher 21 d BW than birds fed diets with multi-toxins alone (P<0.05), 575 g vs. 512 g, while the unchallenged control had the highest body weight (748 g, P<0.05). Feed intake at day 21 followed the same pattern as BW (P<0.05). Feed to gain increased with the multi-toxins challenge from 1.537 to 1.699 (P<0.05), Feeding Calibrin Z, but not Product Y, resulted in a F:G that was not different from the unchallenged control (1.638, P>0.05). Relative liver weight was higher (P<0.05) in the challenged control (5.01 %) compared to the unchallenged control (2.84 %), and Calibrin-Z (4.46 %) but not Product Y (5.12 %) (P<0.05). Blood was collected on d 21 and serum was analyzed for malondialdehyde (MDA, mg/g protein) and total protein. Calibrin Z (4.81) and Product Y (4.37) groups decreased (P<0.05) serum MDA vs. multi-toxins challenge group (7.31). For serum total protein, only Product Y show an improvement, 3.91 vs. 2.19 (P<0.05). In conclusion, adding Calibrin-Z but not product Y to a diet containing multi-toxins improved weight gain, feed intake, and relative liver weight compared to the challenged control.